I think the new technology with mRNA is, as you say, going to open the door to new solutions. Despite some saying it's new and untested, it isn't actually that "new" in that research has been carried out for at least 20 years on just this type of vaccine, and in fact I understand that a SARS vaccine was developed using this technology in around 2003. SARS is a coronavirus, similar to but just a little different from the current version that is so devastating.
My vaccines were both AstraZeneca. There have been a few incidents of death caused by blood clotting; not many. Of course that is a sad loss to the families of the deceased, and I don't belittle that. However, those people may well have died anyway, whether covid related or not. And the fact is that millions of people have been vaccinated with AZ and they've had no problems at all. I can certainly speak for the UK, where there has been a mix of AZ (traditional method) and Pfizer (new mRNA method) and both have been extremely effective at preventing serious illness and especially death. Of those hospitalised, somewhat over 80% are unvaccinated; of the less than 20% vaccinated, they are rarely in the most serious condition or die.
I will be getting a booster jab next week and that will be Pfizer.
In the summer this year, I served as a volunteer vaccination steward in a mass vax centre, and in a couple of months we did 55,000 vaxes, all age groups. Many came in singing and dancing (I jest not; these were older people who got dressed up for this, their first outing in a year!); they were delighted at getting vaxed as a release from the lockdown that we enduring during the previous 12-15 months. We also had many walk-ups (often of younger people not yet eligible) just in case there was a little vaccine still available at the end of the session.
I don't know what you have in mind to discuss, Bolshevik, but I really don't understand the vaccine-averse lot, who seem to listen to fantasy theories and not to people who actually know the science, or have seen outcomes in hospitals. I only know one person who refuses to get an anti-covid vaccine of any type, and he's into some weird ideas about other things as well.
mRNA vaccines are also being developed to deal with various cancers. One might wonder if the vaccine-hesitant for covid might be equally as hesitant if they had an aggressive cancer and a new mRNA vax was likely to be the most successful way to treat that.