The overall concept and several names in this film appear to be taken from the Doc Savage pulp magazines of the 1930s and 1940s: both main characters are multi-talented surgeons, adventurers, and musicians; and both have an inner circle of sidekicks with nicknames.
The movie's ending invites the viewer to watch for the upcoming film "[Title character] vs. The World Crime League". This was the real title for a sequel that Sherwood Studios planned to make, if this film had been successful. Unfortunately, it was a box-office bomb, and Sherwood Studios went bankrupt. However, after its release on video and cable, the film became a cult favorite, much in the same way as Mad Max (1979) (which crawled from obscurity to spawn two sequels). Legal wrangling, due to the bankruptcy, prevented any other studios from picking up the sequel rights, and even many years later, MGM had to fight through a pile of red tape simply to get the OK to re-release it onto home video (DVD). In 2021, the novel "[Title character] Against the World Crime League" was finally released.